√ Circulatory and Heart Health
√ Superior Fibrin Degradation
√ Blood Cleansing and Purification
√ Normal Blood Viscosity
√ Softened Blood Plasma
√ Healthy Plasmin Production
Many Asian cultures exhibit superior cardiovascular health in comparison to average US adults, which is widely attributed to a diet higher in natural food-based enzymes. For instance, the Japanese have consumed a dish known as natto for centuries which contains the heart healthy enzyme nattokinase. Nattovéna is the world's strongest pure-nattokinase product on the market, rated at 4,000 fibrinolytic (fibrin-dissolving) units of activity per capsule. Nattovéna supports circulatory and heart health by assisting in cleansing the body of potentially harmful blood-borne particulates such as fibrin. Fibrin is a protein that develops in excess as we age, which may hinder circulatory function or even impact healthy blood viscosity. Nattovéna is a powerful blood-cleansing enzyme, formulated to help maintain normal cardiovascular health.
Nattokinase: The Natural Blood Thinner that Supports Healthy Blood Pressure, Without Side Effects
Discover the Japanese secret to longevity and cardiovascular health!
The Japanese live longer and healthier than most other people on earth. According to the World Health Organization, not only can Japanese women and men expect to live 86 and 79 years respectively (compared to 80 and 75 years for Americans), but they can also anticipate an average of 75 years of healthy living. One of the reasons are they eat a diet high in fish, vegetables, rice and fermented soy products. As a result, they have a very low incidence of cardiovascular disease.
They also eat natto, a cheese-like product from fermented soybeans. According to Japanese folklore, ancient Samurai warriors consumed natto on a daily basis, and also fed it to their horses to increase agility, power and speed. Natto has been used for more than a thousand years in Japan as a folk remedy for fatigue, dysentery, heart and vascular diseases. It is still very popular in Japan where the annual consumption is approximately four and a half pounds per person.
In 1980 Dr. Hiroyuki Sumi at the University of Chicago Medical School discovered that nattokinase, an enzyme inside natto, supports healthy blood circulation and is effective for preventing blood clots from forming and for dissolving clots that have already formed. Natto reduces the level of fibrin (the protein that accumulates inside blood vessels and clogs them), and helps restore healthy circulation to diseased blood vessels.1
Since most Americans find nattos smell and taste repulsive, its best to take nattokinase in a dietary supplement.
Korean study: nattokinase reduces hypertension
A recent 8-week, randomized double-blind study examined the effects of nattokinase supplementation on 86 untreated adults with high blood pressure. The participants ranged from 20 to 80 years old, and had a systolic blood pressure of 130 to 159. Systolic pressure is the number on top, (i.e. 120/80) which measures the pressure inside your blood vessels at the moment your heart beats.
The participants were given either a placebo or one capsule of 100 mg. of nattokinase each day. By the end of the trial, blood pressure declined approximately 13/5 mm Hg in the group that received nattokinase, compared with baseline. Compared with the placebo group, those who were given nattokinase showed a statistically significant decline in blood pressure of 5.5/2.8 mm Hg. The reduction in blood pressure confirms previous findings from preliminary studies in rats and case studies in humans, and illustrates how nattokinase supplementation can play an important role in preventing and treating hypertension without side effects.2
- 4,000 FU's Per Capsule
- 180 Capsules Pharmaceutical Grade
- Dietary Supplement
- Non GMO
- Kosher Star-K
- ASE - Acid Stable Enzymes
Directions: Take Nattovena with 8 oz of water on an empty stomach. Higher doses may be divided into 2 or 3 servings per day, but it is recommended to not exceed 9 capsules in any 24-hour period unless otherwise directed by a healthcare practitioner.*
Maintenance: 2 Capsules per day.*
Increased Support: 4 Capsules per day.*
Therapeutic: 6 Capsules per day.*
Nattovena is the worlds first ultra-concentrated 4,000 FU pure nattokinase dietary supplement, in easy-to-swallow micro-caps.
Nattovena contains ultra-refined, pharmaceutical grade, acid stable nattokinase. Nattovéna's potency is unparalleled in its class. The standard for nattokinase manufacturing is a potency of up to 2,000 FUs, or fibrinolytic units, of fibrin degrading activity per capsule. Nattovena has broken the mold by providing 4,000 FUs of activity, or double the ordinary dose, offering the strongest nattokinase activity per capsule, period.
Nattovena is specifically formulated to address fibrin imbalances in the body. Fibrin is a protein that plays a major role in blood clotting and scar formation, making it an essential component of the healing process and vital for maintaining our health and general well-being. However, fibrin overproduction and impaired fibrin degradation has been implicated in many of todays most common circulatory health concerns.
What is Nattokinase?
Nattokinase is a fibrinolytic (fibrin-dissolving) enzyme originally discovered within a Japanese fermented soybean food called natto. The dish consists of soybeans fermented with a strain of Bacillus subtilis bacteria that in turn produce the enzyme, which upon its discovery was later named after the respective dish. The fermented dish, natto, has a slimy texture, sour taste and strong smell that is very unappealing to some. Despite its questionable taste, natto has been shown in numerous studies to have many health benefits. For its use in nutritional supplements, the nattokinase enzyme is extracted and purified in a laboratory setting.
Nattovena provides twice the potency of ordinary nattokinase products available and is naturally acid stable in the stomach since it is derived from a food source. This gives Nattovena the added benefit of not having to use an enteric coating or plastic to protect it from stomach acid. Nattovenas formula contains the highest Fibrinolytic Unit (FU) activity among the major brands of nattokinase supplements, allowing it to hydrolyze 4,000 units of fibrin per capsule, thereby optimizing its cardiovascular benefits and promoting normal blood viscosity.
How Does Nattokinase Work?
Fibrin is naturally produced in the body by a protein called thrombin and is degraded by the body's own fibrinolytic enzyme, plasmin. Fibrin is typically produced during the recovery and healing processes caused by injury or other health concerns. Usually, these processes exist in a delicate balance; however, many conditions can impair fibrin degradation and lead to excessive levels of fibrin within the body. Nattokinase supplementation can tip the balance back in favor of fibrin removal using two different mechanisms.
Firstly, nattokinase is a fibrinolytic enzyme, which means that it can literally dissolve excessive fibrin produced during the healing process. In fact, studies show that nattokinase is actually four times (4x) more potent than the bodys own plasmin in terms of fibrinolytic activity1. Secondly, nattokinase blocks the activity of plasminogen activator inhibitor 1 (PAI-1), which boosts its fibrinolytic capabilities even more. High levels of PAI-1 are directly linked to impaired fibrin degradation and removal, since PAI-1 blocks the bodys natural production of plasmin. By impeding PAI-1, nattokinase promotes the creation of more plasmin from plasminogen (its building block), increasing the amount of natural fibrinolytic enzymes created within the body2.
Clinical studies on nattokinase have demonstrated that nattokinase reduces the concentration of fibrinogen within the blood plasma of healthy adults. Examination of blood taken from patients supplementing oral nattokinase revealed the presence of the enzyme intact that was functionally capable of degrading fibrinogen, the building block of fibrin. Thereby nattokinase has been directly shown in a clinical setting to work throughout the body (the circulatory system) as opposed to within the confines of the digestive tract.
Cardiovascular health is the area where nattokinase has probably proven to be the most beneficial. The significance of this effect cannot be understated, especially since cardiovascular disease is the leading cause of death in the United States. Although there are around 20 enzymes in the body which are responsible for creating blood clots, there is only one enzyme, plasmin, which is responsible for dissolving them. As we age though, the production of plasmin slows down and the body is unable to dissolve clots as easily. In addition to a decrease in plasmin production, we also experience an increase in fibrinogen levels. When the levels of fibrinogen increase, platelet aggregation also increases along with an increased risk in blood clots forming throughout the body3. Anyone with these types of cardiovascular risk factors should consider adding nattokinase to their diet. Research on this enzyme has demonstrated that it has an unmatched ability to control these natural imbalances as we age, providing much needed support to the cardiovascular system.
Frequently Asked Questions
What does Nattovena do?
Studies have demonstrated that nattokinase improves overall circulation, promotes healthy blood viscosity, promotes healthy clotting factors, keeps blood cells from sticking together, and maintains blood pressure levels already within normal range.*
How does it work?
Nattovena supports normal clot formation by maintaining normal levels of blood coagulation factors.* It also supports normal clot breakdown by maintaining normal fibrinolytic (clot-dissolving) activity, due to its ability to also increase the production of the body's inherent fibrinolytic enzyme plasmin.*
Why is fibrinolytic activity important?
Fibrin is a vital protein that forms in response to trauma, injury, or even in cases of autoimmune conditions. The body can not only overproduce fibrin in these instances, but can also produce fibrin when there is no trauma or injury, which can lead to a bevy of unwanted symptoms. Fibrinolytic activity is the bodys natural way of breaking up excessive fibrin and unwanted clots.
Is Nattovena safe?
Nattokinase is derived from natto, which has been a regular food staple within Asian cuisine for centuries. Although nattokinase has many benefits, studies have shown that it also does not have demonstrative side effects, and the ingredient is considered GRAS (generally recognized as safe) within the US.
Does Nattovena have value beyond just heart health?
Due to the vast array of unhealthy conditions that excessive fibrin can bring, Nattovena has far greater value than a simple cardiovascular support product. Many aspects of health, from muscle recovery, to immune and joint health are directly related to fibrin and blood viscosity.*
Is Nattovena safe to use in combination with prescription blood-thinning drug medication?
You should always check with your health care provider prior to taking any new dietary supplements in combination with a prescription. However, Nattovena does not contain any vitamin K, so it is assumed to be compatible with these medications since their mode of action is based on inhibiting vitamin K. Nattovena is not contraindicated with aspirin, natural supplements, or antihypertensive medications although medical supervision when implementing any new supplement regimen is always recommended.
SUGGESTED USE Take 1 capsule 2 to 3 times daily on an empty stomach. Higher doses may be taken as needed, but it is recommended to not exceed 15 capsules in any 24-hour period unless otherwise directed by a healthcare practitioner.
WARNING: Do not take this product without the consent of your physician if you are currently taking blood thinning medications or if you are pregnant or nursing.
A fibrinolytic enzyme that can help to maintain normal blood viscosity and normal cardiovascular health.* Nattovena is the only 4,000 FU per capsule product on the market. Nattokinase can support healthy fibrin concentrations.* It has antioxidant effects that may be beneficial to promote normal prostate health, and aids in the elimination of free radicals.*